Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 13/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060125 | 0.89 | TNFRSF1A (0.46) | TNFRSF1ACTSDTUBB4ATUBBTUBA3C | |
| SCHEMBL6988580 | 0.76 | TNFRSF1A (0.59) | TNFRSF1ACTSDTUBB4ATUBBTUBA3C | |
| SCHEMBL5575972 | 0.73 | TNFRSF1A (0.83) | TNFRSF1ACTSD | |
| SCHEMBL5575969 | 0.73 | TNFRSF1A (0.83) | TNFRSF1ACTSD | |
| SCHEMBL5575706 | 0.73 | TNFRSF1A (0.81) | TNFRSF1ACTSD | |
| SCHEMBL5575712 | 0.73 | TNFRSF1A (0.81) | TNFRSF1ACTSD | |
| SCHEMBL5571675 | 0.72 | TNFRSF1A (0.86) | TNFRSF1ACTSD | |
| SCHEMBL5571672 | 0.72 | TNFRSF1A (0.86) | TNFRSF1ACTSD | |
| SCHEMBL5574921 | 0.71 | TNFRSF1A (0.85) | TNFRSF1ACTSD | |
| SCHEMBL5574931 | 0.71 | TNFRSF1A (0.85) | TNFRSF1ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330448-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | Atherogenics, Inc. (US) | 2003-07-30 | — | — | EP | disclosed |
| WO-2001098291-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | ATHEROGENICS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |