Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822360 | 0.92 | ADORA1 (0.44) | ADORA1TP53POLBMAPK1IGF1R | |
| SCHEMBL6818390 | 0.92 | ADORA1 (0.44) | ADORA1TP53POLBMAPK1IGF1R | |
| SCHEMBL6818870 | 0.91 | ADORA1 (0.43) | ADORA1TP53POLBMAPK1IGF1R | |
| SCHEMBL6822479 | 0.91 | TP53 (0.45) | ADORA1TP53POLBIGF1RMAPT | |
| SCHEMBL6824283 | 0.90 | ADORA1 (0.42) | ADORA1TP53POLBMAPK1LMNA | |
| SCHEMBL6822610 | 0.90 | ADORA1 (0.42) | ADORA1TP53POLBMAPK1IGF1R | |
| SCHEMBL6818403 | 0.87 | ADORA1 (0.40) | ADORA1TP53POLBIGF1R | |
| SCHEMBL6822191 | 0.85 | ADORA1 (0.45) | ADORA1TP53POLBMAPK1MAPT | |
| SCHEMBL6825096 | 0.84 | ADORA1 (0.39) | ADORA1TP53POLBMAPK1IGF1R | |
| SCHEMBL6818544 | 0.83 | ADORA1 (0.46) | ADORA1TP53POLBMAPK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |