Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784909 | 0.98 | MAPT (0.63) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL29540859 | 0.87 | NPC1 (0.57) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL16914759 | 0.87 | NPC1 (0.57) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL15478266 | 0.86 | MAPT (0.67) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5027039 | 0.86 | MAPT (0.63) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11372271 | 0.86 | MAPT (0.63) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9342707 | 0.86 | MAPT (0.63) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9296572 | 0.85 | KDM4E (0.57) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28607456 | 0.84 | MAPT (0.61) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| Zinc Ion SCHEMBL5015955 | 0.84 | MAPT (0.61) | MAPTALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006376-B2 | Regioselectively substituted cellulose esters and films made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2024-06-11 | — | — | US | disclosed |
| US-20230235093-A1 | REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND FILMS MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2023-07-27 | — | — | US | disclosed |
| US-11643477-B2 | Regioselectively substituted cellulose esters and films made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2023-05-09 | — | — | US | disclosed |
| EP-3445813-B1 | REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND FILMS MADE THEREFROM | EASTMAN CHEM CO (US) | 2023-02-22 | — | — | EP | disclosed |
| US-11034776-B2 | Regioselectively substituted cellulose esters and films made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2021-06-15 | — | — | US | disclosed |
| US-10759872-B2 | Regioselectively substituted cellulose esters and films made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2020-09-01 | — | — | US | disclosed |
| US-20200223946-A1 | REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND FILMS MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2020-07-16 | — | — | US | disclosed |
| US-10640577-B2 | Regioselectively substituted cellulose esters and films made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20170306054-A1 | REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND FILMS MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170307796-A1 | REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND FILMS MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2017-10-26 | — | — | US | disclosed |
| WO-2010124082-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010124112-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | disclosed |
| US-20100216844-A1 | Carboxamide compounds and their use as calpain inhibitors | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2010-08-26 | — | — | US | disclosed |
| WO-2010094755-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2010-08-26 | — | — | WO | disclosed |
| EP-2173174-A1 | FARNESOID X RECEPTOR AGONISTS | GlaxoSmithKline LLC (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009120826-A1 | 2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | WYETH (US) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009005998-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-01-08 | — | — | WO | disclosed |
| US-4556411-A | Benzothiazole derivatives for plant growth and development modification | FMC CORPORATION (US) | 1985-12-03 | — | — | US | disclosed |
| US-4065427-A | Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4000148-A | POLYMERS | EASTMAN KODAK COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216844-A1 | Carboxamide compounds and their use as calpain inhibitors | CAMK4, CAMK2A, CAMK2B | MAPT 393/4885ALDH1A1 4543/4885NPC1 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.