Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.79 |
| ▸ | FNTB | P49356 | 13/20 | 0.79 |
| ▸ | SLC6A15 | Q9H2J7 | 8/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | PTAFR | P25105 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999519 | 0.90 | FNTA (0.69) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL7002862 | 0.88 | FNTA (1.00) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL7003550 | 0.85 | FNTA (1.00) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6993307 | 0.83 | FNTA (1.00) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6997676 | 0.80 | FNTA (0.81) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL8127745 | 0.79 | FNTA (0.78) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9374487 | 0.76 | PTAFR (0.73) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6991647 | 0.76 | FNTA (1.00) | FNTAFNTBSLC6A15 | |
| SCHEMBL6993193 | 0.76 | FNTA (0.79) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6997386 | 0.76 | FNTA (0.84) | FNTAFNTBSLC6A15HRH1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |