Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 11/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775680 | 0.91 | ADORA1 (0.54) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6771685 | 0.86 | HPGD (0.52) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6769069 | 0.85 | ADORA1 (0.48) | ADORA1ADORA2AADORA2BCTSSMEN1 | |
| SCHEMBL6770039 | 0.84 | PIK3R1 (0.52) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6770608 | 0.83 | ADORA1 (0.46) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6775541 | 0.82 | ADORA1 (0.52) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6774916 | 0.82 | ADORA1 (0.51) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6768976 | 0.82 | ADORA2A (0.60) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6768602 | 0.81 | ADORA1 (0.48) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL6765760 | 0.81 | ADORA1 (0.64) | ADORA1ADORA2AADORA2BMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308441-A1 | 2-AMINOPYRIDINE COMPOUNDS AND USE THEREOF AS DRUGS | Eisai Co., Ltd. (JP) | 2003-05-07 | — | — | EP | disclosed |