Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMG1 | Q96Q15 | 7/20 | 0.61 |
| ▸ | CDK1 | P06493 | 4/20 | 0.61 |
| ▸ | CDK2 | P24941 | 4/20 | 0.61 |
| ▸ | CAMK2D | Q13557 | 6/20 | 0.55 |
| ▸ | MTOR | P42345 | 3/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987209 | 0.85 | SMG1 (0.62) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL6097424 | 0.82 | SMG1 (0.57) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL6095496 | 0.80 | SMG1 (0.59) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL6098077 | 0.80 | SMG1 (0.58) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL6109641 | 0.78 | SMG1 (0.78) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL28749736 | 0.78 | SMG1 (0.56) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL27580808 | 0.76 | SMG1 (0.66) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL6093641 | 0.76 | SMG1 (0.66) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL6107663 | 0.76 | SMG1 (1.00) | SMG1CDK1CDK2CAMK2DMTOR | |
| SCHEMBL5630858 | 0.74 | SMG1 (0.65) | SMG1CDK1CDK2CAMK2DMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349849-A1 | MICROBIOCIDAL N-PHENYL-N-[4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | Syngenta Participations AG (CH) | 2003-10-08 | — | — | EP | claimed |
| WO-2002053560-A1 | MICROBIOCIDAL N-PHENYL-N-[4-(4-PYRIDYL-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-07-11 | — | — | WO | claimed |