Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.51 |
| ▸ | HRH1 | P35367 | 19/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5109347 | 0.88 | HRH1 (0.61) | CCR3HRH1KCNH2 | |
| SCHEMBL4718927 | 0.81 | HRH1 (0.72) | CCR3HRH1KCNH2 | |
| SCHEMBL6242779 | 0.81 | HRH1 (0.72) | CCR3HRH1KCNH2 | |
| SCHEMBL20570794 | 0.78 | HRH1 (0.50) | CCR3HRH1KCNH2 | |
| SCHEMBL10606839 | 0.78 | HRH1 (0.58) | CCR3HRH1KCNH2 | |
| SCHEMBL215117 | 0.77 | HRH1 (0.49) | CCR3HRH1KCNH2 | |
| SCHEMBL27900147 | 0.77 | HRH1 (0.49) | CCR3HRH1KCNH2 | |
| SCHEMBL22462743 | 0.77 | HRH1 (0.49) | CCR3HRH1KCNH2 | |
| SCHEMBL14413679 | 0.76 | HRH1 (0.57) | CCR3HRH1KCNH2 | |
| SCHEMBL21722932 | 0.76 | HRH1 (0.48) | CCR3HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289956-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001092227-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-12-06 | — | — | WO | disclosed |