Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924881 | 0.97 | AR (0.66) | ARPGR | |
| SCHEMBL8926483 | 0.94 | AR (0.60) | ARPGR | |
| SCHEMBL8173477 | 0.91 | AR (0.73) | ARPGR | |
| SCHEMBL8924486 | 0.89 | AR (0.62) | ARPGR | |
| SCHEMBL7819446 | 0.89 | AR (0.73) | ARPGR | |
| SCHEMBL7819080 | 0.89 | AR (0.54) | ARPGR | |
| SCHEMBL633896 | 0.88 | AR (0.67) | ARPGR | |
| SCHEMBL7818235 | 0.86 | AR (0.53) | ARPGR | |
| SCHEMBL8926413 | 0.85 | AR (0.53) | ARPGR | |
| Ru-58841 SCHEMBL29372187 | 0.83 | AR (1.00) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877738-B1 | PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES | AVENTIS PHARMA SA (FR) | 2003-05-14 | — | — | EP | claimed |
| EP-0704448-B1 | Heterocyclic substituted imidazolidines, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | claimed |
| US-6107488-A | MAKING 3-(3-TRIFLUOROMETHYLPHENYL) HYDANTOIN DERIVATIVES BY PREPARING 1-(HALO OR HYDANTOIN),3-(TRIFLUOROMETHYL),4-AMINO-BENZENE DERIVATIVES AND SUBJECTING THEM TO VARIOUS REACTIONS | HOECHST MARION ROUSSEL (FR) | 2000-08-22 | — | — | US | claimed |
| US-5705654-A | ANTIANDROGENS | ROUSSEL UCLAF (FR) | 1998-01-06 | — | — | US | claimed |
| US-5646172-A | Method of inducing antiandrogenic activity using imidazolidines substituted with a heterocycle | ROUSSEL UCLAF (FR) | 1997-07-08 | — | — | US | claimed |
| JP-8099977-A | — | — | None | — | — | JP | disclosed |
| EP-0877738-B1 | PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES | AVENTIS PHARMA SA (FR) | 2003-05-14 | — | — | EP | disclosed |
| US-6107488-A | MAKING 3-(3-TRIFLUOROMETHYLPHENYL) HYDANTOIN DERIVATIVES BY PREPARING 1-(HALO OR HYDANTOIN),3-(TRIFLUOROMETHYL),4-AMINO-BENZENE DERIVATIVES AND SUBJECTING THEM TO VARIOUS REACTIONS | HOECHST MARION ROUSSEL (FR) | 2000-08-22 | — | — | US | disclosed |
| US-5958936-A | FOR INDUCING ANTIANDROGENIC ACTIVITY IN WARM-BLOODED ANIMALS, INCLUDING HUMANS | HOECHST MARION ROUSSEL (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0877738-A1 | NEW PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | disclosed |
| US-5705654-A | ANTIANDROGENS | ROUSSEL UCLAF (FR) | 1998-01-06 | — | — | US | disclosed |
| US-5646172-A | Method of inducing antiandrogenic activity using imidazolidines substituted with a heterocycle | ROUSSEL UCLAF (FR) | 1997-07-08 | — | — | US | disclosed |
| WO-1997018197-A1 | NEW PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-05-22 | — | — | WO | disclosed |
| JP-H0899977-A | NEW IMIDAZOLIDINE SUBSTITUTED WITH HETEROCYCLE, ITS PRODUCTION AND INTERMEDIATE, ITS USE AS MEDICINE AND PREPARATION COMPOSITION CONTAINING THE SAME | ROUSSEL UCLAF | 1996-04-16 | — | — | JP | disclosed |