Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6999558 | 0.99 | SMN1; SMN2 (0.38) | CCNA2CDK2CDK5CDK5R1LMNA | |
| Hydrochloric Acid SCHEMBL6990604 | 0.99 | SMN1; SMN2 (0.38) | CCNA2CDK2CDK5CDK5R1LMNA | |
| Hydrochloric Acid SCHEMBL6993455 | 0.99 | SMN1; SMN2 (0.38) | CCNA2CDK2CDK5CDK5R1LMNA | |
| SCHEMBL7831053 | 0.88 | MAP4K1 (0.36) | CCNA2CDK2CDK5CDK5R1LMNA | |
| SCHEMBL6991378 | 0.88 | AXL (0.35) | HTTKDM4EALDH1A1 | |
| SCHEMBL7831079 | 0.88 | MAP4K1 (0.36) | CCNA2CDK2CDK5CDK5R1LMNA | |
| SCHEMBL6997579 | 0.88 | AXL (0.35) | HTTKDM4EALDH1A1 | |
| SCHEMBL7835067 | 0.88 | MCHR1 (0.36) | CCNA2CDK2CDK5CDK5R1LMNA | |
| Hydrochloric Acid SCHEMBL6993609 | 0.87 | AXL (0.34) | HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6991842 | 0.87 | AXL (0.34) | HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |