⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13282806 | 1.00 | — | — | |
| SCHEMBL13282805 | 1.00 | — | — | |
| SCHEMBL22208015 | 0.81 | ATM (0.46) | — | |
| SCHEMBL10951685 | 0.81 | — | — | |
| SCHEMBL3677891 | 0.81 | USP2 (0.50) | — | |
| SCHEMBL11950437 | 0.80 | — | — | |
| SCHEMBL12310728 | 0.80 | — | — | |
| SCHEMBL12310672 | 0.80 | — | — | |
| SCHEMBL9226670 | 0.79 | — | — | |
| SCHEMBL103387 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006035-B1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NEUPHARMA INC (US) | 2023-11-22 | — | — | EP | disclosed |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| EP-4006035-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Neupharma, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |
| EP-2953457-B1 | ERK INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2020-04-08 | — | — | EP | disclosed |
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |
| US-9796700-B2 | ERK inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2017-10-24 | — | — | US | disclosed |
| US-4772744-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4662935-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| US-4613360-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| US-4478838-A | VASODILATOR AGENTS | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1984-10-23 | — | — | US | disclosed |
| US-4422868-A | PLANT GROWTH REGULATORS | ROHM AND HAAS COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4415354-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-15 | — | — | US | disclosed |
| EP-0083712-A1 | 1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives and a process for the preparation thereof | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1983-07-20 | — | — | EP | disclosed |
| US-4330324-A | PREEMERGENCE APPLICATION | ROHM AND HAAS COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4220468-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4093446-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-06-06 | — | — | US | disclosed |