Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | MPC2 | O95563 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184708 | 0.96 | FFAR1 (0.60) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6185090 | 0.93 | FFAR1 (0.52) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6478590 | 0.90 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6183176 | 0.90 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6472881 | 0.88 | FFAR1 (0.57) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6477719 | 0.88 | FFAR1 (0.57) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5762703 | 0.88 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6473690 | 0.88 | FFAR1 (0.58) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6480099 | 0.88 | FFAR1 (0.58) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6183075 | 0.87 | HSD17B2 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |