SCHEMBL699208

SCHEMBL699208

O=C(/C=C/c1ccccc1)N[C@H]1CCCC[C@@H]1NC(=O)/C=C/c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.65
HPGD P15428 2/20 0.65
HDAC3 O15379 2/20 0.58
HDAC4 P56524 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
HDAC6 Q9UBN7 2/20 0.58
CYP1A2 P05177 1/20 0.54
EGFR P00533 2/20 0.53
MMP1 P03956 2/20 0.53
MMP2 P08253 2/20 0.53
MMP9 P14780 2/20 0.53
MAOB P27338 2/20 0.53
MAOA P21397 1/20 0.53
KMT2A Q03164 2/20 0.51
HTT P42858 2/20 0.51
MEN1 O00255 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MAPT P10636 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11904296 1.00 SMN1; SMN2 (0.65) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL12971486 0.91 MAPK1 (0.61) SMN1; SMN2HPGDHDAC2CYP1A2EGFR
SCHEMBL6381757 0.91 SMN1; SMN2 (0.59) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL6381822 0.91 SMN1; SMN2 (0.59) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL6381833 0.91 SMN1; SMN2 (0.59) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL6381827 0.91 SMN1; SMN2 (0.59) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL692584 0.87 CYP1A2 (0.70) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL692583 0.87 CYP1A2 (0.70) SMN1; SMN2HPGDHDAC3HDAC4HDAC1
SCHEMBL28891768 0.85 CYP1A2 (0.73) SMN1; SMN2CYP1A2MAOBHTTDRD2
SCHEMBL13169532 0.85 CYP1A2 (0.73) SMN1; SMN2CYP1A2MAOBHTTDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2466582-B1 Optical Data Storage Media And Methods For Using The Same GEN ELECTRIC (US) 2014-02-26 EP claimed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 EP claimed
EP-2290408-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-08-15 EP claimed
US-8182967-B2 Optical data storage media and methods for using the same GENERAL ELECTRIC COMPANY (US) 2012-05-22 US claimed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US claimed
US-8778568-B2 Optical data storage media and methods for using the same GENERAL ELECTRIC COMPANY (US) 2014-07-15 US disclosed
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 US disclosed
EP-2466582-B1 Optical Data Storage Media And Methods For Using The Same GEN ELECTRIC (US) 2014-02-26 EP disclosed
US-8507153-B2 Compositions, optical data storage media and methods for using the optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-08-13 US disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 EP disclosed
US-8343608-B2 Use of appended dyes in optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-01-01 US disclosed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 EP disclosed
EP-2423917-A2 Use of chemically bonded dyes in holographic data storage media General Electric Company (US) 2012-02-29 EP disclosed
US-8124299-B2 Methods for using optical data storage media GENERAL ELECTRIC COMPANY (US) 2012-02-28 US disclosed
US-20110051586-A1 OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
US-20110053054-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290650-A1 Optical data storage media and methods for using the same General Electric Company (US) 2011-03-02 EP disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed