⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924268 | 1.00 | — | — | |
| SCHEMBL2202738 | 1.00 | — | — | |
| SCHEMBL1929406 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL31706459 | 0.79 | — | — | |
| SCHEMBL523741 | 0.79 | — | — | |
| SCHEMBL204179 | 0.79 | — | — | |
| SCHEMBL7934771 | 0.79 | — | — | |
| SCHEMBL9397884 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6131906 | 0.76 | — | — | |
| SCHEMBL303459 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 559 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346935-A1 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE | CODEXIS, INC. (US) | 2025-11-13 | — | — | US | claimed |
| US-12378585-B2 | Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | claimed |
| US-20240229091-A1 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE | CODEXIS INC (US) | 2024-07-11 | — | — | US | claimed |
| CN-118185892-A | Short-chain dehydrogenase and application thereof in synthesis of (R) -tetrahydrothiophene-3-alcohol | 河北工业大学 | 2024-06-14 | — | — | CN | claimed |
| CN-115745953-B | Hydroxyl fluoro reagent and hydroxyl fluoro method | 上海凌凯医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| US-11965194-B2 | Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane | CODEXIS, INC. (US) | 2024-04-23 | — | — | US | claimed |
| CN-116768850-A | 3-hydroxy sulfolane derivative and its synthesis and application as lithium ion battery electrolyte additive | 研一(杭州)新能源科技有限责任公司 | 2023-09-19 | — | — | CN | claimed |
| US-20230068040-A1 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2023-03-02 | — | — | US | claimed |
| US-11427841-B2 | Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane | CODEXIS, INC. (US) | 2022-08-30 | — | — | US | claimed |
| US-20210054426-A1 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-02-25 | — | — | US | claimed |
| WO-2004069827-A1 | QUINOLINE DERIVATIVES AND USE THEREOF AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2004-08-19 | — | — | WO | claimed |
| EP-1444210-A1 | QUNAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2004-08-11 | — | — | EP | claimed |
| EP-1444211-A2 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2004-08-11 | — | — | EP | claimed |
| WO-2003047584-A1 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003048159-A1 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003040108-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2003-05-15 | — | — | WO | claimed |
| WO-2003040109-A2 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2003-05-15 | — | — | WO | claimed |
| EP-0479541-B1 | Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith | TAKASAGO PERFUMERY CO LTD (JP) | 1995-07-19 | — | — | EP | claimed |
| US-5159093-A | IRIDIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-10-27 | — | — | US | claimed |
| EP-0479541-A1 | Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith | Takasago International Corporation (JP) | 1992-04-08 | — | — | EP | claimed |