Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992384 | 1.00 | MEN1 (0.40) | MEN1KMT2AHRH3ALDH1A1TSHR | |
| Oxalic Acid SCHEMBL6997385 | 0.96 | KMT2A (0.47) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL6997388 | 0.96 | KMT2A (0.47) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL6998748 | 0.88 | KMT2A (0.49) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL7001732 | 0.88 | KMT2A (0.49) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| SCHEMBL6997176 | 0.82 | KDM4E (0.47) | MEN1KMT2AHRH3ALDH1A1TSHR | |
| SCHEMBL6999792 | 0.82 | KDM4E (0.47) | MEN1KMT2AHRH3ALDH1A1TSHR | |
| Oxalic Acid SCHEMBL6996239 | 0.80 | KDM4E (0.51) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL6991315 | 0.80 | KDM4E (0.51) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL6996106 | 0.79 | HRH3 (0.57) | MEN1KMT2AHRH3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | claimed |
| EP-0853615-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1998-07-22 | — | — | EP | claimed |
| WO-1997010212-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-03-20 | — | — | WO | claimed |
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |