Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | ATM | Q13315 | 2/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798962 | 0.89 | SLC2A1 (0.76) | POLBATMSLC2A1SMN1; SMN2SMPD1 | |
| SCHEMBL11811971 | 0.89 | SLC2A1 (0.68) | POLBATMSLC2A1SMN1; SMN2SMPD1 | |
| SCHEMBL7435099 | 0.88 | ATM (0.76) | POLBATMSLC2A1SMN1; SMN2SMPD1 | |
| SCHEMBL2845264 | 0.87 | ATM (0.80) | POLBATMSMN1; SMN2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11808765 | 0.87 | ATM (0.73) | POLBATMSLC2A1SMN1; SMN2KDM4E | |
| SCHEMBL30230461 | 0.87 | ATM (1.00) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8635081 | 0.87 | ATM (1.00) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL557799 | 0.87 | ATM (1.00) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28670719 | 0.86 | SLC2A1 (0.64) | POLBATMSLC2A1SMN1; SMN2SMPD1 | |
| Hydrochloric Acid SCHEMBL3657276 | 0.85 | ATM (0.96) | POLBATMSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003749-B1 | 8-SUBSTITUTED-9H-1,3-DIOXOLO/4,5-h/2,3/BENZODIAZEPINE DERIVATES, AS AMPA/KAINATERECEPTOR INHIBITORS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-10-22 | — | — | EP | disclosed |
| US-6562810-B1 | Competitive AMPA/kainite antagonist properties making them useful in the treatment of diseases where inhibition of the AMPA/kainite receptors may a favorable effect | EGIS GYOGYSZERGYAR RT. (HU) | 2003-05-13 | — | — | US | disclosed |
| US-5430059-A | Treating heart disease | EISAI CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |