Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.79 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991924 | 0.90 | NPY5R (0.88) | NPY5RUSP30NPC1RAB9A | |
| SCHEMBL6992743 | 0.88 | NPY5R (1.00) | NPY5RUSP30NPC1RAB9A | |
| SCHEMBL6992742 | 0.86 | NPY5R (1.00) | NPY5RUSP30NPC1RAB9AFLT3 | |
| SCHEMBL6991126 | 0.86 | NPY5R (0.78) | NPY5RUSP30NPC1RAB9ACDK2 | |
| SCHEMBL6990465 | 0.86 | NPY5R (0.95) | NPY5RUSP30NPC1RAB9A | |
| SCHEMBL6997030 | 0.86 | NPY5R (0.73) | NPY5RUSP30NPC1RAB9AFLT3 | |
| SCHEMBL6999633 | 0.86 | NPY5R (0.82) | NPY5RCDK2 | |
| SCHEMBL6999024 | 0.86 | NPY5R (0.73) | NPY5RUSP30NPC1RAB9AFLT3 | |
| SCHEMBL6989342 | 0.84 | NPY5R (0.73) | NPY5RUSP30CCNA2CDK2CCNA1 | |
| SCHEMBL6995503 | 0.84 | NPY5R (0.73) | NPY5RUSP30NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |