Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179686 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL394409 | 0.95 | — | — | |
| Hydrogen Sulfide SCHEMBL27338739 | 0.95 | — | — | |
| Acetic Acid SCHEMBL28732456 | 0.91 | GAA (0.54) | — | |
| SCHEMBL28943494 | 0.89 | GAA (0.52) | — | |
| SCHEMBL28766202 | 0.89 | GAA (0.52) | — | |
| SCHEMBL22971022 | 0.89 | GAA (0.52) | — | |
| Nitric Acid SCHEMBL28766191 | 0.85 | GAA (0.48) | — | |
| SCHEMBL18207666 | 0.83 | GAA (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL30924176 | 0.83 | GAA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339692-A1 | NOVEL COMPOUNDS FOR USE AS HIV PROTEASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002042277-A1 | NOVEL COMPOUNDS FOR USE AS HIV PROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-30 | — | — | WO | disclosed |