Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 19/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217778 | 0.91 | CCR3 (0.71) | CCR3HTR2ACCR5 | |
| SCHEMBL6329419 | 0.86 | CCR3 (0.69) | CCR3HTR2A | |
| SCHEMBL6331131 | 0.76 | CCR3 (0.69) | CCR3HTR2A | |
| SCHEMBL6330867 | 0.75 | CCR3 (0.84) | CCR3HTR2A | |
| SCHEMBL7813834 | 0.74 | CCR3 (0.72) | CCR3HTR2A | |
| SCHEMBL6215640 | 0.73 | CCR3 (1.00) | CCR3HTR2A | |
| SCHEMBL6333237 | 0.73 | CCR3 (0.61) | CCR3CCR5 | |
| SCHEMBL6993094 | 0.73 | CCR3 (0.62) | CCR3HTR2A | |
| SCHEMBL6337783 | 0.73 | CCR3 (1.00) | CCR3HTR2A | |
| SCHEMBL6701753 | 0.72 | CCR3 (1.00) | CCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363881-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2001098269-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |