Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998880 | 0.92 | DRD1 (0.41) | ACHEBACE1BCHESIGMAR1DRD1 | |
| SCHEMBL6998873 | 0.92 | DRD1 (0.41) | ACHEBACE1BCHESIGMAR1DRD1 | |
| SCHEMBL6998889 | 0.92 | DRD1 (0.41) | ACHEBACE1BCHESIGMAR1DRD1 | |
| SCHEMBL1597738 | 0.91 | DRD1 (0.42) | ACHEBACE1BCHESLC6A12SIGMAR1 | |
| SCHEMBL1597736 | 0.91 | DRD1 (0.42) | ACHEBACE1BCHESLC6A12SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7000122 | 0.91 | DRD1 (0.40) | ACHEBACE1BCHESIGMAR1DRD1 | |
| Hydrochloric Acid SCHEMBL7000132 | 0.91 | DRD1 (0.40) | ACHEBACE1BCHESIGMAR1DRD1 | |
| Hydrochloric Acid SCHEMBL7000125 | 0.91 | DRD1 (0.40) | ACHEBACE1BCHESIGMAR1DRD1 | |
| Fumaric Acid SCHEMBL7142414 | 0.87 | HTR2A (0.40) | ACHEBACE1BCHESLC6A12SIGMAR1 | |
| Fumaric Acid SCHEMBL7142418 | 0.87 | HTR2A (0.40) | ACHEBACE1BCHESLC6A12SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |