Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138362 | 0.90 | ADORA1 (0.74) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5712840 | 0.89 | ADORA1 (0.76) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7001600 | 0.87 | ADORA1 (0.67) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7000426 | 0.87 | ADORA1 (0.62) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6998249 | 0.87 | ADORA1 (0.70) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7001243 | 0.87 | ADORA1 (0.70) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5678867 | 0.86 | ADORA1 (0.71) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6992778 | 0.85 | ADORA1 (0.67) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16007300 | 0.85 | ADORA1 (0.80) | ADORA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL12608918 | 0.84 | ADORA1 (0.82) | ADORA1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087977-B1 | THIENODIPYRIDINE DERIVATIVES, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6214838-B1 | WHICH ARE STABLE TO METABOLISM BY THE BODY AND EXHIBITS ANTI-INFLAMMATORY ACTIVITY, BONE RESORPTION INHIBITORY ACTIVITY AND ACTIVITY IN INHIBITING PRODUCTION OF IMMUNOCYTOKINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-1087977-A1 | THIENODIPYRIDINE DERIVATIVES, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065916-A1 | THIENODIPYRIDINE DERIVATIVES, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-23 | — | — | WO | disclosed |