Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993423 | 1.00 | DRD1 (0.40) | DRD1KDM4EHPGDSMN1; SMN2PARP1 | |
| SCHEMBL6988724 | 1.00 | DRD1 (0.40) | DRD1KDM4EHPGDSMN1; SMN2PARP1 | |
| SCHEMBL1596458 | 0.90 | DRD1 (0.40) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL1596456 | 0.90 | DRD1 (0.40) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL6988755 | 0.85 | DRD1 (0.38) | DRD1SMN1; SMN2PARP1 | |
| SCHEMBL6996299 | 0.85 | DRD1 (0.40) | DRD1KDM4EHPGDSMN1; SMN2PARP1 | |
| SCHEMBL6988760 | 0.85 | DRD1 (0.38) | DRD1SMN1; SMN2PARP1 | |
| SCHEMBL6988766 | 0.85 | DRD1 (0.38) | DRD1SMN1; SMN2PARP1 | |
| SCHEMBL6996305 | 0.85 | DRD1 (0.40) | DRD1KDM4EHPGDSMN1; SMN2PARP1 | |
| SCHEMBL6997554 | 0.85 | DRD1 (0.40) | DRD1KDM4EHPGDSMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |