Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812115 | 0.84 | GAA (0.48) | KDM4EELANEESR2MAPTALDH1A1 | |
| SCHEMBL14829419 | 0.81 | CYP1A1 (0.48) | KDM4EELANETHRBMAPTMAOB | |
| SCHEMBL10790308 | 0.79 | KDM4E (0.55) | KDM4EMAPTMAOAHSD17B3ALDH1A1 | |
| SCHEMBL31485738 | 0.79 | ELANE (0.47) | KDM4EELANEESR2MAPTMAOA | |
| SCHEMBL11308108 | 0.78 | GAA (0.53) | KDM4EELANEMAPTALDH1A1GAA | |
| SCHEMBL17177077 | 0.78 | KDM4E (0.49) | KDM4EELANEALDH2ESR2MAPT | |
| SCHEMBL9205430 | 0.77 | ELANE (0.37) | ELANEALDH2ESR2ACHEALDH1A1 | |
| SCHEMBL17637914 | 0.76 | KDM4E (0.56) | KDM4EELANEESR2MAPTMAOA | |
| SCHEMBL17166803 | 0.76 | CYP2A6 (0.43) | ELANEACHEALDH1A1 | |
| SCHEMBL15069107 | 0.74 | CCR4 (0.49) | ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376244-C | Use of non-steroidal sulfamate compounds for preparing medicine for treating tumor | STERIX LTD (GB) | 2008-03-26 | — | — | CN | disclosed |
| CN-1989961-A | Use of non-steroidal sulfamate compound in the prepararion of drug for treating tumor | STERIX LTD (GB) | 2007-07-04 | — | — | CN | disclosed |
| CN-1701790-A | Use of non-steroidal sulfamate compounds for preparing medicine for treating tumor | STERIX LTD (GB) | 2005-11-30 | — | — | CN | disclosed |
| EP-1032265-B1 | NEW PSORALENS FOR PATHOGEN INACTIVATION | CERUS CORP (US) | 2003-10-29 | — | — | EP | disclosed |