SCHEMBL6993604

SCHEMBL6993604

CC(C)(C)OC(=O)N1CCC(CC(=O)N2CCN(C3c4ccc(Cl)cc4SCc4cccnc43)CC2)CC12OO2

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.70
FNTB P49356 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7001210 0.88 FNTA (0.81) FNTAFNTB
SCHEMBL7001590 0.83 FNTA (1.00) FNTAFNTB
SCHEMBL6999519 0.82 FNTA (0.69) FNTAFNTB
SCHEMBL7002444 0.80 FNTA (1.00) FNTAFNTB
SCHEMBL8137180 0.80 FNTA (0.78) FNTAFNTB
SCHEMBL7000838 0.79 FNTA (1.00) FNTAFNTB
SCHEMBL7000164 0.78 FNTA (0.81) FNTAFNTB
SCHEMBL6997327 0.74 FNTA (0.78) FNTAFNTB
SCHEMBL7000549 0.74 FNTA (1.00) FNTAFNTB
SCHEMBL7002993 0.73 FNTA (0.78) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1021448-B1 TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS SCHERING CORP (US) 2003-05-02 EP disclosed
US-6130229-A Tricyclic compounds having activity as RAS-FPT inhibitors SCHERING CORPORATION (US) 2000-10-10 US disclosed