Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7995916 | 0.99 | F2 (0.48) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6992688 | 0.94 | F2 (0.50) | F2PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL7989441 | 0.93 | F2 (0.49) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6992076 | 0.93 | F2 (0.49) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6995649 | 0.93 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6998939 | 0.93 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7003096 | 0.93 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL7989226 | 0.92 | F2 (0.49) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6994960 | 0.92 | F2 (0.49) | F2PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL7996215 | 0.92 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |