Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 12/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.56 |
| ▸ | F2 | P00734 | 9/20 | 0.56 |
| ▸ | F10 | P00742 | 12/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570346 | 0.88 | F10 (0.47) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL27589110 | 0.81 | F10 (0.44) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL7600977 | 0.78 | F10 (0.58) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL7450111 | 0.76 | F10 (0.72) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL5885649 | 0.76 | F2 (0.77) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL7114685 | 0.76 | F10 (0.70) | PRSS1F2F10PLGPLAT | |
| SCHEMBL7067776 | 0.76 | F10 (0.61) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL7072812 | 0.76 | F10 (0.64) | PRSS1PRSS2PRSS3F2F10 | |
| Hydrochloric Acid SCHEMBL5885248 | 0.75 | F2 (0.76) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL7069811 | 0.74 | F10 (0.59) | PRSS1PRSS2PRSS3F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309573-A1 | URETHANE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-05-14 | — | — | EP | claimed |
| WO-2002010145-A1 | URETHANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | WO | claimed |