Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129849 | 0.85 | SLC6A4 (0.56) | HTR1ADRD2HTR7HTR6SLC6A4 | |
| SCHEMBL6994354 | 0.85 | SLC6A4 (0.56) | HTR1ADRD2HTR7HTR6SLC6A4 | |
| SCHEMBL6994351 | 0.85 | SLC6A4 (0.56) | HTR1ADRD2HTR7HTR6SLC6A4 | |
| Hydrochloric Acid SCHEMBL8382216 | 0.84 | SLC6A4 (0.58) | HTR1ADRD2HTR7HTR6SLC6A4 | |
| SCHEMBL6998384 | 0.84 | JAK2 (0.47) | HTR1ADRD2HTR7HTR6SLC6A4 | |
| SCHEMBL6999439 | 0.84 | SLC6A4 (0.56) | SLC6A4 | |
| SCHEMBL1122232 | 0.84 | HTR1D (0.43) | SLC6A4 | |
| SCHEMBL6999444 | 0.84 | SLC6A4 (0.56) | SLC6A4 | |
| SCHEMBL6996253 | 0.83 | SLC6A4 (0.56) | HTR1ADRD2HTR7HTR6SLC6A4 | |
| SCHEMBL6996256 | 0.83 | SLC6A4 (0.56) | HTR1ADRD2HTR7HTR6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562809-B1 | Contraction of coronary arteries may be mediated by its stimulation of the 5-HT1B (formerly 5-HT1D beta); compounds selective for a 5-HT1D receptor | NPS ALLELIX CORP. (CA) | 2003-05-13 | — | — | US | claimed |
| EP-1114049-B1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-03-19 | — | — | EP | claimed |
| EP-1114049-B1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-03-19 | — | — | EP | disclosed |