Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.46 |
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | PPARD | Q03181 | 12/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995735 | 0.89 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL5105508 | 0.84 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL5099341 | 0.79 | PPARG (0.67) | PPARAPPARGPPARD | |
| SCHEMBL7139083 | 0.74 | PPARG (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5105209 | 0.73 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL7139081 | 0.71 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL5112892 | 0.71 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL7139077 | 0.71 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL6958967 | 0.70 | PPARG (0.44) | PPARAPPARG | |
| SCHEMBL14176222 | 0.69 | PPARA (0.56) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |