⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20805099 | 0.87 | — | — | |
| SCHEMBL29111594 | 0.85 | — | — | |
| SCHEMBL19545983 | 0.85 | — | — | |
| SCHEMBL17448293 | 0.84 | — | — | |
| SCHEMBL16250329 | 0.83 | — | — | |
| SCHEMBL16250310 | 0.83 | — | — | |
| SCHEMBL16412133 | 0.79 | — | — | |
| SCHEMBL6998834 | 0.78 | — | — | |
| SCHEMBL23288390 | 0.77 | — | — | |
| SCHEMBL22047823 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293562-A1 | THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF | SAPREME TECHNOLOGIES B.V. (NL) | 2023-09-21 | — | — | US | disclosed |
| US-20230265438-A1 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | ASOCIACION CENTRO DE INVESTIG COOPERATIVA EN BIOCIENCIAS CIC BIOGUNE (ES) | 2023-08-24 | — | — | US | disclosed |
| EP-4223315-A2 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | Ionis Pharmaceuticals, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-4219712-A2 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL | Silence Therapeutics GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219718-A2 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | Ionis Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023078273-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078021-A1 | BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023066236-A1 | AGT INHIBITOR AND USE THEREOF | 厦门甘宝利生物医药有限公司 | 2023-04-27 | — | — | WO | disclosed |
| EP-3608406-B1 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | IONIS PHARMACEUTICALS INC (US) | 2023-02-15 | — | — | EP | disclosed |
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |
| US-8183355-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-05-22 | — | — | US | disclosed |
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-10-06 | — | — | US | disclosed |
| US-7951926-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-05-31 | — | — | US | disclosed |
| US-7862807-B2 | Dendrimers as molecular translocators | UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2011-01-04 | — | — | US | disclosed |
| US-20100233190-A1 | TARGETED POLYMERIC PRODRUGS CONTAINING MULTIFUNCTIONAL LINKERS | ENZON PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100160409-A1 | Highly Branched Reagents For Modifying Biopharmaceuticals, Their Preparation And Use | CELARES GMBH (DE) | 2010-06-24 | — | — | US | disclosed |
| US-20090124571-A1 | METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-05-14 | — | — | US | disclosed |
| US-20080221020-A1 | Dendrimers as Molecular Translocators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-11 | — | — | US | disclosed |
| US-7262221-B2 | Amphiphilic star-like macromolecules for drug delivery | RUTGERS THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262221-B2 | Amphiphilic star-like macromolecules for drug delivery | RUTGERS THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-08-28 | — | — | US | disclosed |