Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579376 | 0.81 | GSK3B (0.43) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3579382 | 0.81 | GSK3B (0.43) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3579379 | 0.81 | GSK3B (0.43) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3568800 | 0.80 | GSK3B (0.41) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4576867 | 0.79 | GSK3B (0.40) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3570579 | 0.78 | GSK3B (0.42) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3570581 | 0.78 | GSK3B (0.42) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3570578 | 0.78 | GSK3B (0.42) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3567718 | 0.77 | GSK3B (0.46) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL6223005 | 0.77 | GSK3B (0.45) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340760-A1 | Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives | SANOFI-SYNTHELABO (FR) | 2003-09-03 | — | — | EP | disclosed |
| EP-1295884-A1 | 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]Pyrimidin-4-one and 7-Pyrimidinyl-2,3-Dihydroimidazo[1,2-a]Pyrimidin-5(1H)one derivatives | SANOFI-SYNTHELABO (FR) | 2003-03-26 | — | — | EP | disclosed |