SCHEMBL699591

SCHEMBL699591

CC(=O)OC1c2ccc(OCc3cccc(-c4c(C)nc(OCCC(C)(C)O)nc4C)c3C)cc2CC12CC2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 17/20 0.36
FFAR1 O14842 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563281 0.87 FFAR1 (0.39) CD274FFAR1
SCHEMBL10203910 0.86 CD274 (0.37) CD274FFAR1
SCHEMBL562002 0.78 CD274 (0.45) CD274FFAR1
SCHEMBL10203925 0.77 CD274 (0.42) CD274FFAR1
SCHEMBL563019 0.76 FFAR1 (0.38) CD274FFAR1
SCHEMBL562609 0.76 CD274 (0.41) CD274FFAR1
SCHEMBL10203920 0.76 FFAR1 (0.43) CD274FFAR1
SCHEMBL10203804 0.76 CD274 (0.36) CD274FFAR1
SCHEMBL10203850 0.76 FFAR1 (0.40) CD274FFAR1
SCHEMBL562643 0.75 FFAR1 (0.36) CD274FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423176-A1 CARBOXYLIC ACID COMPOUND Astellas Pharma Inc. (JP) 2012-02-29 EP claimed