Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998823 | 0.85 | CCR1 (0.46) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL7000468 | 0.81 | CCR1 (0.47) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL6996406 | 0.81 | CCR1 (0.42) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL7000678 | 0.78 | CCR1 (0.50) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL6993764 | 0.78 | CCR1 (0.61) | CCR1FPR3GPR65GPR35CCR3 | |
| SCHEMBL6993694 | 0.77 | CCR1 (0.43) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL7001038 | 0.76 | MEN1 (0.45) | CCR1FPR3GPR65GPR35CCR3 | |
| SCHEMBL6997012 | 0.76 | KDM4E (0.52) | CCR1SMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL6996562 | 0.75 | POLB (0.54) | CCR1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6760369 | 0.72 | CCR1 (0.45) | CCR1FPR3GPR65GPR35PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326867-A2 | BRIDGED PIPERAZINE DERIVATIVES | Pfizer Products Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032901-A2 | BRIDGED PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2002-04-25 | — | — | WO | disclosed |