Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098838 | 0.77 | KCNH2 (0.43) | S1PR1PTGDR2SYKAURKBINCENP | |
| SCHEMBL5089110 | 0.77 | FNTA (0.42) | S1PR1PTGDR2SYKAURKBINCENP | |
| SCHEMBL5089060 | 0.77 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL6991437 | 0.76 | CYP2A6 (0.64) | CYP2A6CHRNB4CHRNA3CHRNA7CA2 | |
| SCHEMBL5089214 | 0.76 | FNTA (0.47) | S1PR1PTGDR2SYKAURKBINCENP | |
| SCHEMBL5099574 | 0.76 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL5098841 | 0.76 | FNTA (0.48) | PTGDR2 | |
| SCHEMBL5091309 | 0.75 | PTGDR2 (0.45) | S1PR1PTGDR2SYKAURKBINCENP | |
| SCHEMBL5094116 | 0.75 | FNTA (0.47) | PTGDR2SYK | |
| SCHEMBL5091227 | 0.74 | PGGT1B (0.44) | S1PR1PTGDR2SYKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339695-A1 | FARNESYLTRANSFERASE INHIBITORS | Abbott Laboratories (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002074747-A1 | FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-09-26 | — | — | WO | disclosed |