Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.78 |
| ▸ | MAOA | P21397 | 5/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.78 |
| ▸ | SDHA | P31040 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | CALML3 | P27482 | 1/20 | 0.78 |
| ▸ | F10 | P00742 | 8/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994115 | 1.00 | MAOB (0.78) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6992080 | 0.93 | MAOB (0.79) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6992074 | 0.93 | MAOB (0.79) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6991510 | 0.92 | MAOB (0.76) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6991516 | 0.92 | MAOB (0.76) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6993645 | 0.91 | MAOB (0.75) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6993651 | 0.91 | MAOB (0.75) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6191297 | 0.90 | MAOB (0.80) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6995056 | 0.90 | MAOB (0.80) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6995061 | 0.90 | MAOB (0.80) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750618-B1 | OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UPJOHN CO (US) | 2003-02-19 | — | — | EP | claimed |
| EP-0750618-B1 | OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UPJOHN CO (US) | 2003-02-19 | — | — | EP | disclosed |
| US-5668286-A | ANTIBIOTIC | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-16 | — | — | US | disclosed |