Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 17/20 | 0.69 |
| ▸ | GRIN3B | O60391 | 17/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 17/20 | 0.69 |
| ▸ | GRIN2A | Q12879 | 17/20 | 0.69 |
| ▸ | GRIN2B | Q13224 | 17/20 | 0.69 |
| ▸ | GRIN2C | Q14957 | 17/20 | 0.69 |
| ▸ | GRIN3A | Q8TCU5 | 17/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998175 | 0.82 | GRIN2D (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6440019 | 0.82 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8572631 | 0.79 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL6992609 | 0.77 | GRIN2D (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6995040 | 0.77 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL6992603 | 0.76 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6993523 | 0.76 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6398081 | 0.75 | KDM6B (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6992293 | 0.75 | GRIN1 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL6997010 | 0.75 | GRIN2D (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| CN-1102144-C | Noval pyrimidine derivatives and prepn. processes thereof | YUHAN CORP (KR) | 2003-02-26 | — | — | CN | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| CN-1155281-A | Noval pyrimidine derivatives and prepn. processes thereof | YUHAN CORP (KR) | 1997-07-23 | — | — | CN | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |