Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.67 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.67 |
| ▸ | CCR7 | P32248 | 1/20 | 0.55 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865057 | 0.92 | CXCR2 (0.69) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6865051 | 0.92 | CXCR2 (0.69) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6869265 | 0.87 | CXCR2 (0.76) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6864156 | 0.84 | CXCR2 (0.69) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6869113 | 0.84 | CXCR2 (0.80) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL842950 | 0.83 | CXCR2 (0.77) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6865142 | 0.83 | CXCR2 (0.77) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6865459 | 0.82 | CXCR2 (0.74) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL841656 | 0.81 | CXCR2 (0.81) | CXCR2CXCR1CCR7CX3CR1 | |
| SCHEMBL6866679 | 0.81 | CXCR2 (0.67) | CXCR2CXCR1CCR7CX3CR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104425-B1 | NOVEL THIAZOLOPYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | claimed |