Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | ERBB4 | Q15303 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992496 | 0.86 | EGFR (0.69) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL3473824 | 0.85 | EGFR (0.76) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6989676 | 0.85 | EGFR (0.76) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8318913 | 0.85 | EGFR (0.66) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7584741 | 0.85 | EGFR (0.66) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7584754 | 0.85 | EGFR (0.66) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7578092 | 0.85 | EGFR (0.66) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7578117 | 0.85 | EGFR (0.66) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8314263 | 0.85 | EGFR (0.84) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7580715 | 0.85 | EGFR (0.65) | EGFRERBB2HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888351-B1 | PYRIMIDO 5,4-D]PYRIMIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION | THOMAE GMBH DR K (DE) | 2003-10-15 | — | — | EP | disclosed |