Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318688 | 0.89 | EGFR (0.73) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL8318694 | 0.89 | EGFR (0.73) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6993919 | 0.88 | EGFR (0.71) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6995102 | 0.87 | EGFR (0.76) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL8314263 | 0.87 | EGFR (0.84) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6995784 | 0.87 | EGFR (0.70) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6993292 | 0.86 | EGFR (0.71) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6993876 | 0.85 | EGFR (0.72) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6993885 | 0.85 | EGFR (0.72) | EGFRERBB2HPGDHTTCSNK2A1 | |
| SCHEMBL6999264 | 0.85 | EGFR (0.65) | EGFRERBB2HPGDHTTCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888351-B1 | PYRIMIDO 5,4-D]PYRIMIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION | THOMAE GMBH DR K (DE) | 2003-10-15 | — | — | EP | disclosed |