Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.57 |
| ▸ | PPARA | Q07869 | 16/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431366 | 0.91 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5103119 | 0.90 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL14431770 | 0.89 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL5105744 | 0.88 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5105917 | 0.87 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5112981 | 0.87 | PPARA (0.68) | PPARGPPARAPPARD | |
| SCHEMBL5099360 | 0.84 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL5105604 | 0.84 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5098184 | 0.83 | PPARA (0.68) | PPARGPPARAPPARD | |
| SCHEMBL14431464 | 0.82 | PPARG (0.61) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |