Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 18/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 17/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7996089 | 0.99 | F10 (0.40) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7001946 | 0.98 | F10 (0.41) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7995781 | 0.97 | F10 (0.41) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6991520 | 0.94 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6997893 | 0.94 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6994205 | 0.94 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7992373 | 0.94 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7992079 | 0.94 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7996059 | 0.94 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6995334 | 0.90 | F2 (0.43) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |