Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.60 |
| ▸ | PPARA | Q07869 | 13/20 | 0.60 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997565 | 0.89 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL6996099 | 0.88 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL6993797 | 0.87 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL6702379 | 0.85 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL5106039 | 0.85 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL5214674 | 0.85 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL5106040 | 0.82 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL5111702 | 0.82 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL5112747 | 0.82 | PPARA (0.70) | PPARGPPARAPPARD | |
| SCHEMBL14431461 | 0.82 | PPARG (0.60) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |