Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996910 | 0.84 | P2RY12 (0.63) | P2RY12 | |
| SCHEMBL6990483 | 0.84 | P2RY12 (0.51) | P2RY12ADORA3ADORA2AADORA1 | |
| SCHEMBL6990484 | 0.84 | P2RY12 (0.51) | P2RY12ADORA3ADORA2AADORA1 | |
| SCHEMBL6994243 | 0.83 | P2RY12 (0.51) | P2RY12 | |
| SCHEMBL5729000 | 0.81 | P2RY12 (0.48) | P2RY12ADORA3 | |
| SCHEMBL5729273 | 0.79 | P2RY12 (0.48) | P2RY12ADORA3 | |
| SCHEMBL5729274 | 0.79 | P2RY12 (0.48) | P2RY12ADORA3 | |
| Carbamic Acid SCHEMBL7510846 | 0.78 | P2RY12 (0.66) | P2RY12 | |
| Bicarbonate SCHEMBL7507037 | 0.78 | P2RY12 (0.68) | P2RY12 | |
| SCHEMBL5728835 | 0.76 | P2RY12 (0.70) | P2RY12ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056749-B1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LTD (GB) | 2003-02-19 | — | — | EP | claimed |