Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 15/20 | 0.63 |
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.40 |
| ▸ | CCR7 | P32248 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512329 | 0.93 | CXCR2 (0.73) | CXCR2CX3CR1CCR7 | |
| SCHEMBL7515242 | 0.88 | CXCR2 (0.61) | CXCR2CX3CR1CCR7 | |
| SCHEMBL7004972 | 0.86 | CXCR2 (0.71) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3859363 | 0.84 | CXCR2 (0.86) | CXCR2CCR7 | |
| SCHEMBL3851666 | 0.83 | CXCR2 (0.75) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3851663 | 0.83 | CXCR2 (0.75) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3851449 | 0.79 | CXCR2 (0.73) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3850892 | 0.79 | CXCR2 (0.83) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3851505 | 0.79 | CXCR2 (0.71) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3849120 | 0.78 | CXCR2 (0.68) | CXCR2CX3CR1CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259512-B1 | PTERIDINE COMPOUNDS FOR THE TREATMENT OF PSORIASIS | ASTRAZENECA AB (SE) | 2003-09-24 | — | — | EP | claimed |