Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.68 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.68 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 3/20 | 0.66 |
| ▸ | XDH | P47989 | 2/20 | 0.66 |
| ▸ | P4HB | P07237 | 1/20 | 0.66 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000261 | 1.00 | F3 (0.75) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL3687467 | 0.92 | F3 (0.66) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL599211 | 0.92 | F3 (0.66) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL599210 | 0.92 | F3 (0.66) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL3687472 | 0.92 | F3 (0.66) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL10938612 | 0.90 | F3 (0.64) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL10938616 | 0.90 | F3 (0.64) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL28342974 | 0.90 | F3 (0.64) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL11879138 | 0.90 | F3 (0.68) | F3MAPTALDH1A1HPGDMAOB | |
| SCHEMBL11879134 | 0.90 | F3 (0.68) | F3MAPTALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921119-B1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0921119-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-09 | — | — | EP | disclosed |
| EP-0071165-B1 | UNSATURATED ARYL KETONES AS ANTISEBORRHOEIC ADDITIVES FOR COSMETIC COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-09-04 | — | — | EP | disclosed |
| US-4439418-A | UNSATURATED ARYL KETONE | HENKEL KGAA (DE) | 1984-03-27 | — | — | US | disclosed |
| EP-0071165-A1 | Unsaturated aryl ketones as antiseborrhoeic additives for cosmetic compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-02-09 | — | — | EP | disclosed |