Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998889 | 0.86 | DRD1 (0.41) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL6998880 | 0.86 | DRD1 (0.41) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL6998873 | 0.86 | DRD1 (0.41) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7000132 | 0.86 | DRD1 (0.40) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7000125 | 0.86 | DRD1 (0.40) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7000122 | 0.86 | DRD1 (0.40) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL6998755 | 0.83 | DRD1 (0.43) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL6998747 | 0.83 | DRD1 (0.43) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL6998751 | 0.83 | DRD1 (0.43) | SIGMAR1HTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL27562876 | 0.83 | PARP1 (0.34) | ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | claimed |
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |