⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026 | 0.97 | — | — | |
| SCHEMBL3475223 | 0.97 | — | — | |
| SCHEMBL9027 | 0.97 | — | — | |
| SCHEMBL10679392 | 0.97 | TSHR (0.39) | — | |
| SCHEMBL25341328 | 0.94 | — | — | |
| SCHEMBL9765097 | 0.94 | — | — | |
| SCHEMBL967188 | 0.94 | — | — | |
| Water SCHEMBL1204298 | 0.94 | — | — | |
| Methane SCHEMBL22130032 | 0.94 | — | — | |
| SCHEMBL30244934 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925292-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING SUBSTITUTED CHROMANOL DERIVATIVES | PFIZER (US) | 2003-09-10 | — | — | EP | disclosed |
| CN-1394602-A | Benzoic acid substituted benzopyran fro curing atheroscleorsis | PFIZER (US) | 2003-02-05 | — | — | CN | disclosed |
| EP-1270000-A2 | Benzoic acid substituted benzopyrans for the treatment of atherosclerosis | Pfizer Products Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6444826-B1 | REACTING HYDROXYCHROMAN-BENZOIC ACID DERIVATIVE WITH BASE | PFIZER INC. | 2002-09-03 | — | — | US | disclosed |
| US-20020099227-A1 | Processesand intermediatesfor preparing substitutedchromanol derivatives | PISCOPIO ANTHONY (US) | 2002-07-25 | — | — | US | disclosed |
| US-20020042526-A1 | Processesand intermediatesfor preparing substitutedchromanol derivatives | PISCOPIO ANTHONY (US) | 2002-04-11 | — | — | US | disclosed |
| US-6355825-B1 | REDUCING AGENT, SUCH AS LITHIUM BOROHYDRIDE, LITHIUM ALUMINUM HYDRIDE, SODIUM BOROHYDRIDE OR CALCIUM BOROHYDRIDE FOR TREATMENT OF SKIN DISORDERS AND INFLAMMATION | PFIZER INC. | 2002-03-12 | — | — | US | disclosed |
| US-6288242-B1 | DIHYDROXY COMPOUNDS WITH AROMATIC RINGS ANTIARTHRITIC AGENTS | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |
| US-6096906-A | PREPARING CARBOXYPHENYLCHROMANOLS BY REACTING ALKOXYCARBONYLPHENYLCHROMANOLS WITH A BASE | PFIZER INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0925292-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING SUBSTITUTED CHROMANOL DERIVATIVES | PFIZER INC. (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011085-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING SUBSTITUTED CHROMANOL DERIVATIVES | PFIZER INC. (US) | 1998-03-19 | — | — | WO | disclosed |