Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.64 |
| ▸ | FNTB | P49356 | 12/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001745 | 1.00 | FNTA (0.64) | FNTAFNTBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6994976 | 0.83 | FNTA (0.64) | FNTAFNTBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6994980 | 0.83 | FNTA (0.64) | FNTAFNTBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6995097 | 0.81 | FNTA (0.74) | FNTAFNTB | |
| SCHEMBL6995089 | 0.78 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6995093 | 0.78 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6998378 | 0.77 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL6996211 | 0.76 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL8169075 | 0.74 | FNTA (0.75) | FNTAFNTB | |
| SCHEMBL6995656 | 0.73 | FNTA (0.48) | FNTAFNTBALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |
| EP-1021448-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015556-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |