Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 5/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | FRK | P42685 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
| ▸ | STK3 | Q13188 | 1/20 | 0.60 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.60 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.60 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184953 | 0.88 | KDM4E (0.69) | KDM4ECSF1RROCK2MAP4K4LCK | |
| SCHEMBL4851140 | 0.82 | CSF1R (0.76) | KDM4ECSF1RROCK2MAP4K4LCK | |
| SCHEMBL10647724 | 0.81 | KDM4E (0.63) | KDM4ECSF1RMAPTMEN1KMT2A | |
| SCHEMBL4847744 | 0.81 | MAP2 (0.72) | KDM4ECSF1RROCK2MAP4K4LCK | |
| Hydrochloric Acid SCHEMBL4854389 | 0.80 | MAP2 (0.71) | KDM4ECSF1RROCK2MAP4K4LCK | |
| SCHEMBL4854377 | 0.80 | CSF1R (0.69) | KDM4ECSF1RROCK2MAP4K4LCK | |
| SCHEMBL6059495 | 0.79 | MAP2 (0.74) | KDM4ECSF1RROCK2MAP4K4LCK | |
| SCHEMBL30043560 | 0.79 | MAP2 (0.74) | KDM4ECSF1RROCK2MAP4K4LCK | |
| SCHEMBL8924448 | 0.78 | KDM4E (0.59) | KDM4EMAP2MEN1KMT2ACA1 | |
| SCHEMBL24095581 | 0.78 | KDM4E (0.79) | KDM4ECSF1RROCK2MAP4K4LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6114349-A | Substituted quinoline derivatives with antiviral action | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |