Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.44 |
| ▸ | ABL1 | P00519 | 6/20 | 0.44 |
| ▸ | VCP | P55072 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PSMC4 | P43686 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | YES1 | P07947 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | FRK | P42685 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003897 | 0.80 | SRC (0.42) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL7003040 | 0.79 | SRC (0.41) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL6998124 | 0.77 | SRC (0.55) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL6997527 | 0.74 | SRC (0.46) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL6997533 | 0.74 | SRC (0.46) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL7001439 | 0.72 | SRC (0.44) | SRCABL1VCPHPGDPSMC4 | |
| SCHEMBL7001441 | 0.72 | SRC (0.44) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL7003178 | 0.72 | SRC (0.46) | SRCABL1VCPHPGDSMN1; SMN2 | |
| SCHEMBL7003995 | 0.72 | SRC (0.43) | SRCABL1VCPHPGDPSMC4 | |
| SCHEMBL7000322 | 0.70 | SRC (0.44) | SRCABL1VCPSMN1; SMN2PSMC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140938-B1 | HIGH AFFINITY INHIBITORS FOR TARGET VALIDATION AND USES THEREOF | UNIV PRINCETON (US) | 2003-08-27 | — | — | EP | disclosed |