Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7992460 | 0.99 | F2 (0.52) | F2PRSS1KLKB1MAP4K1PIK3CD | |
| SCHEMBL7298438 | 0.88 | F2 (0.66) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7978194 | 0.87 | F2 (0.65) | F2PRSS1 | |
| SCHEMBL7001605 | 0.87 | F2 (0.54) | F2PRSS1PIK3CD | |
| Hydrochloric Acid SCHEMBL7992275 | 0.86 | F2 (0.54) | F2PRSS1PIK3CD | |
| SCHEMBL6999388 | 0.84 | F2 (0.49) | F2PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL7978078 | 0.84 | F2 (0.49) | F2PRSS1KLKB1 | |
| SCHEMBL7002402 | 0.82 | F2 (0.54) | F2PRSS1 | |
| SCHEMBL6739800 | 0.82 | F2 (0.49) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7989097 | 0.82 | F2 (0.54) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |