Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.77 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002377 | 1.00 | P2RY12 (0.77) | P2RY12AHCY | |
| SCHEMBL6995464 | 0.87 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL6999864 | 0.87 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL6995474 | 0.87 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL7512903 | 0.86 | P2RY12 (0.78) | P2RY12 | |
| SCHEMBL7512896 | 0.86 | P2RY12 (0.78) | P2RY12 | |
| SCHEMBL7475374 | 0.80 | P2RY12 (0.86) | P2RY12 | |
| SCHEMBL7475367 | 0.80 | P2RY12 (0.86) | P2RY12 | |
| SCHEMBL7002539 | 0.80 | P2RY12 (0.70) | P2RY12AHCY | |
| SCHEMBL7002536 | 0.80 | P2RY12 (0.70) | P2RY12AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | claimed |
| US-6251910-B1 | 1,2,3-triazolo[4,5-d]pyrimidines as P2T receptor antagonists | ASTRAZENECA UK LIMITED (GB) | 2001-06-26 | — | — | US | claimed |
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |
| US-6251910-B1 | 1,2,3-triazolo[4,5-d]pyrimidines as P2T receptor antagonists | ASTRAZENECA UK LIMITED (GB) | 2001-06-26 | — | — | US | disclosed |